(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid
[6-(1-hydroxy-1-methyl-ethyl)-3-pyridyl]boronic acid
CAS: 1088496-42-7
Molecular Formula: C8H12BNO3
(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid - Names and Identifiers
(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid - Physico-chemical Properties
| Molecular Formula | C8H12BNO3 |
| Molar Mass | 181 |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD09992916 |
(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid - Introduction
6-(2-hydroxypropan-2-yl) pyridine-3-boronic acid, also known as valine borate (Lysine Boronic Acid), is an organic boron compound.
Nature:
1. Appearance: colorless crystal or crystalline powder.
2. Solubility: Soluble in water and alcohol solvents, insoluble in non-polar solvents.
3. Stability: 6-(2-hydroxy propane -2-yl) pyridine -3-boric acid is relatively stable, but it may decompose under the conditions of high temperature, strong acid and strong alkali.
Use:
1. Valine borate is an important organometallic ligand that can form stable complexes with metal ions. Therefore, it is widely used in the fields of coordination chemistry, metal organic chemistry and catalytic reaction.
2. It can also be used for coupling reactions in organic synthesis, such as Suzuki coupling reaction, Stille coupling reaction, etc.
Preparation Method:
The preparation method of 6-(2-hydroxypropan-2-yl) pyridine-3-boronic acid generally includes the reaction of pyridine and 2-hydroxy-3-bromopropane with tetramethylammonium bromide under alkaline conditions, and The complexation reaction is carried out with alcohol and boric acid or boric acid ester.
Safety Information:
1. 6-(2-hydroxy propane -2-yl) pyridine -3-boric acid has a certain irritation, operation should avoid contact with the skin and eyes, if necessary, should wear protective gloves and goggles.
2. in the use and storage process should avoid contact with strong acid, alkali and other substances, so as not to cause dangerous reaction.
3. in the treatment of waste, should be in accordance with the provisions of the method of disposal, to avoid pollution to the environment.
Nature:
1. Appearance: colorless crystal or crystalline powder.
2. Solubility: Soluble in water and alcohol solvents, insoluble in non-polar solvents.
3. Stability: 6-(2-hydroxy propane -2-yl) pyridine -3-boric acid is relatively stable, but it may decompose under the conditions of high temperature, strong acid and strong alkali.
Use:
1. Valine borate is an important organometallic ligand that can form stable complexes with metal ions. Therefore, it is widely used in the fields of coordination chemistry, metal organic chemistry and catalytic reaction.
2. It can also be used for coupling reactions in organic synthesis, such as Suzuki coupling reaction, Stille coupling reaction, etc.
Preparation Method:
The preparation method of 6-(2-hydroxypropan-2-yl) pyridine-3-boronic acid generally includes the reaction of pyridine and 2-hydroxy-3-bromopropane with tetramethylammonium bromide under alkaline conditions, and The complexation reaction is carried out with alcohol and boric acid or boric acid ester.
Safety Information:
1. 6-(2-hydroxy propane -2-yl) pyridine -3-boric acid has a certain irritation, operation should avoid contact with the skin and eyes, if necessary, should wear protective gloves and goggles.
2. in the use and storage process should avoid contact with strong acid, alkali and other substances, so as not to cause dangerous reaction.
3. in the treatment of waste, should be in accordance with the provisions of the method of disposal, to avoid pollution to the environment.
Last Update：2024-04-09 20:49:11
